What is an important nursing consideration when administering ACE inhibitors?

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Monitoring blood pressure and renal function is crucial when administering ACE inhibitors. ACE inhibitors, such as lisinopril or enalapril, are primarily used to manage hypertension and heart failure. They work by inhibiting the angiotensin-converting enzyme, which reduces the production of angiotensin II, leading to vasodilation and a decrease in blood pressure.

When initiating treatment with ACE inhibitors, close attention is needed to ensure that blood pressure is lowered to the desired therapeutic range and to avoid potential hypotension, especially in patients who are on diuretics or have volume depletion. Furthermore, these medications can affect kidney function, so monitoring renal parameters such as serum creatinine and electrolyte levels is essential. An increase in serum creatinine can indicate renal impairment, which can be precipitated by the medication, primarily in individuals with pre-existing renal conditions or those with dehydration.

This focus on blood pressure and renal assessment ensures safe and effective management of the patient's condition while minimizing risks associated with ACE inhibitor therapy.