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Digoxin toxicity can present with a specific set of symptoms that are critical for healthcare providers to recognize. The most common indicators include gastrointestinal disturbances, such as nausea, vomiting, and diarrhea; cardiac symptoms such as arrhythmias; and neuropsychiatric manifestations such as confusion or altered mental status.

As digoxin affects the heart's electrical activity, it can lead to various types of arrhythmias, which are serious and potentially life-threatening. The gastrointestinal symptoms are often among the first signs of toxicity, while neurological symptoms indicate substantial toxicity that may require immediate intervention.

Although other symptoms can occur with digoxin toxicity, such as visual disturbances or palpitations, the combination of gastrointestinal issues, arrhythmias, and confusion distinctly reflects the serious nature of the toxicity and aligns with the clinical presentation typically observed in cases of digoxin overdose. Understanding these manifestations allows practitioners to act swiftly to mitigate risks and manage patient care effectively.