Which insulin category typically has the longest duration of action?

Lantus, also known as insulin glargine, is an insulin analog that is specifically designed to have a prolonged duration of action. It provides a steady release of insulin over a 24-hour period, which helps to maintain consistent blood glucose levels throughout the day and night. This long-lasting effect makes it particularly beneficial for patients who require basal insulin to manage their blood sugar effectively.

In contrast, other insulin types like Humalog (a rapid-acting insulin) are designed for quick onset and shorter duration, primarily used to control blood sugar spikes following meals. NPH (neutral protamine Hagedorn) is an intermediate-acting insulin that has a duration of action typically ranging from 10 to 16 hours, and Regular insulin has a shorter duration, usually around 6 to 8 hours, with a peak action that is also relatively brief. Thus, when considering the insulin categories, Lantus stands out for its extended period of action, making it the preferred choice for providing a baseline level of insulin.